Journal: EJNMMI Research
Article Title: Evaluation of the theranostic potential of [ 64 Cu]CuCl 2 in glioblastoma spheroids
doi: 10.1186/s13550-024-01084-8
Figure Lengend Snippet: Cellular uptake of [ 64 Cu]CuCl 2 in spheroids derived from glioblastoma and astrocyte cell lines. Cellular uptake was measured at 1, 2, and 3 h after incubation with 0.09 MBq of [ 64 Cu]CuCl 2 . Uptake values were normalized to the spheroids' mean area of each cell line and the maximum uptake measured at 1 h in U87 spheroids. Data are presented as mean values ± S.E.M. of 3 to 5 independent assays. * p < 0.05, ** p < 0.01
Article Snippet: Rat Astrocytes (RA) were obtained from Cell Applications, Inc.. T98G and U87 cell lines were cultured in Minimum Essential Medium (MEM) with GlutaMAXTM (Gibco, Thermo Fisher Scientific) supplemented with 10% fetal bovine serum (FBS) (Gibco, Thermo Fisher Scientific).
Techniques: Derivative Assay, Incubation